💨 Abstract

Researchers from the University of Cologne have found that a specific variant of the tau protein, 1N4R isoform, causes harmful effects in Alzheimer's disease by forming protein clumps in human brain cells. The team used human induced pluripotent stem cells (iPSCs), CRISPR/Cas9 gene editing, and live-cell imaging to demonstrate this.

Courtesy: theprint.in

Summarized by Einstein Beta 🤖